Total hip joint endoprosthetics in patient with osteopetrosis. Clinical observation

Rationale: Total hip joint endoprosthetics is the most common way of surgical treatment of hip joint osteoarthrosis. The long-term existence of this method and the development of operative techniques allow minimizing the risks of complications during primary hip joint arthroplasty. However, in case of concomitant pathology with changes in bone density in patients, the risk of fractures increases both at the stage of endoprosthesis installation and in the postoperative period.

Study objective: To identify treatment characteristics and potential technical difficulties during total hip joint endoprosthetics in patients diagnosed with osteopetrosis.

Materials and Methods: This article presents a clinical case of total endoprosthetics in a patient with osteopetrosis and a review of current medical periodicals on this topic.

Conclusion: The materials of this clinical case and literature review are intended to draw the attention of practicing traumatologists and orthopedists to possible difficulties and complications in treatment of patients with osteopetrosis and to prevent intraoperative complications during hip joint endoprosthetics.

1. Papagrigorakis E, Galanis A, Vlachos C, Vavourakis M, Zachariou D, Vlamis J, Pneumaticos S. Periprosthetic fracture of total hip replacement in patients with osteopetrosis: A case presentation and review of literature. J Frailty Sarcopenia Falls. 2022 Dec 1; 7 (4): 251-256. https://doi.org/10.22540/JFSF-07-251 . PMID: 36531518; PMCID: PMC9729755.

2. Zhilyaev VM, Arapova SD, Mamedova EO, Tarbaeva NV, Belaya ZhE. Osteopetrosis: the follow-up of the disease in a patient who underwent hematopoietic stem cell transplantation at the age of 27 years. Osteoporosis and bone diseases. 2020;23(1):14-19. https://doi.org/10.14341/osteo12434

3. Petrushin A.L., Tyusova N.N., Nekhoroshkova T.V. SCLEROTIC OSTEODYSPLASIAS. Traumatology and Orthopedics of Russia. 2016; 22 (1): 136-150. https://doi.org/10.21823/2311-2905-2016-0-1-136-150

4. Wei C, Li H. Total hip arthroplasty for the treatment of a hip disorder complicated by autosomal dominant osteopetrosis: a case report. J Int Med Res. 2023 Jul; 51 (7): 3000605231187803. https://doi.org/10.1177/03000605231187803 . PMID: 37523459; PMCID: PMC10392520.

5. Gao X, Cheng Q, Zhang X, Zhao G. Successful total hip arthroplasty for autosomal dominant osteopetrosis complicated by hip osteoarthritis: A case report and review of the literature. Exp Ther Med. 2020 Apr; 19 (4): 2702-2706. https://doi.org/10.3892/etm.2020.8503 Epub 2020 Feb 10. PMID: 32256752; PMCID: PMC7086189.